Searchable abstracts of presentations at key conferences in endocrinology

ea0081rc11.3 | Rapid Communications 11: Thyroid 2 | ECE2022

Is the pre-conceptional TSH optimization useful in women submitted to assisted reproduction technology?

Maria Vannucchi Guia , Campi Irene , Cagnina Serena , Covelli Danila , Persani Luca , Mignini Renzini Mario , Fugazzola Laura

Background: thyroid function (TSH levels) and thyroid autoimmunity are involved in the immunomodulation of early pregnancy stages and can affect assisted reproductive technology (ART).Aims: 1) to evaluate if pre-conceptional TSH is associated with an increased risk of miscarriage, 2) to identify a TSH cut-off significantly associated with risk of miscarriage, 3) to assess the impact of TSH levels on primary and surrogate outcomes.M...

ea0084ps3-13-118 | Pregnancy & Iodine | ETA2022

Which is the best pre-conceptional TSH cut-off in women submitted to assisted reproductive technology?

Vannucchi Guia , Campi Irene , Cagnina Serena , Covelli Danila , Mignini Renzini Mario , Persani Luca , Fugazzola Laura

TSH is involved in the immunomodulation of early pregnancy stages. Thyroid guidelines have indicated 2.5 mU/l as the best TSH level below which women undergoing assisted reproductive technology (ART) need to be maintained, though this treshold is still controversial. Aims of the present study were to evaluate if pre-conceptional TSH is associated with an increased risk of miscarriage, to identify a TSH cut-off significantly associated with risk of miscarriage and to assess the...

ea0037gp.07.01 | Reproduction: Female and other | ECE2015

Preconceptional TSH and miscarriage in infertile women submitted to IVF

Vannucchi Guia , Covelli Danila , Renzini Mario , Brigante Claudio , Coticchio Giovanni , Canto Maria Beatrice Dal , Fadini Rubens , Dazzi Davide , Negro Roberto , Fugazzola Laura

It is known that high levels of TSH are associated with higher miscarriage risk, though the precise TSH cut-offs are debated. Aim of the present study was to evaluate if pre-conceptional TSH levels associate with increased risk of early miscarriage in a large series of infertile women submitted to IVF and to determine the threshold of TSH associated with the highest prevalence of pregnancy loss. We retrospectively studied 1484 infertile women (mean±age 36.7±4.1 years...